Vape-One is an electronic cigarette store with two locations, the original location was the first vapor store in St. Louis and located in South City. The second is located in Des Peres, Missouri in West County. We are a group of "Vapers" with a passion for our products. We love to help people get started and answer any questions you may have, whether you are new to vaping or an advanced user. 

We believe we carry the best flavors of eliquid at a great value. We research all of the hardware we offer to ensure you get the best quality at the best price.

We share our South City space with our friends: 

One Umbrella Art Gallery and Screen Printing. 
Look for the colorful windows and One Umbrella logo.

About Our eLiquid
All of the eLiquid we sell is made in the USA.
We have over 100 different flavors available in a variety of sizes and strengths. 

All of our eLiquid is made in a laboratory setting. We require strict environmental controls and accuracy in the products we sell. Because we believe that safety and sanitary conditions are so important, we do not mix eLiquid in store. 

Already Making Clouds?

We offer a variety of advanced, top of the line mods, rebuildables, and other devices. We also have wick, wire, ribbon wire, mesh, and more. 

Just Starting Out?

We offer Starter Kits with everything you need (including eliquid) for under $40!  When you come in we will help you with everything  you need to know to begin vaping.

Shop Online!

We've selected some of our favorite and bestselling products and made the available to rest of the world!

South City

4385 Bates. St.
St. Louis, MO 63116

(With One Umbrella Artists)

Mon-Fri: 10am to 8PM
Saturday: 10am to 8PM
Sunday: Noon to 6PM



Des Peres

11823 Manchester Rd.
Des Peres, MO 63131

(At Bopp Rd, next to Remax)

Mon-Fri: 10am to 8PM
Saturday: 10am to 8PM
Sunday: Noon to 6PM



2 Awesome Locations

Vape-One Supports the Efforts of


What Our Customers Are Saying

Current News and Deals
October 20th - 25th

  • Vape-One is hosting an Extra Life event October 25th - More Info Here

  • Flavor of the WeekJester Juice - Jigsaw 20% off (30ml for $8.79)

  • Deal of the WeekIndigo Buy 2 Get 1 Free! (45ml for $19.99)

  • All October - Get (4) 30ml bottles of Jester Juice for $30